6EDL

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6EDL_A

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GENERAL

TITLE

HALK IN COMPLEX WITH COMPOUND 1 (S)-N-(1-(2,4-DIFLUOROPHENYL)ETHYL)-3- (3-METHYL-1H-PYRAZOL-5-YL)IMIDAZO[1,2-B]PYRIDAZIN-6-AMINE

DATE LAST MODIFIED

5 Jun 2019

RELEASE

1 May 2019

OBSOLETE

CLASSIFICATION

TRANSFERASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.8

RESOLUTION RANGE LOW

38.42

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.8B01630

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9UM73	ALK	UNIDENTIFIED BACULOVIRUS	HUMAN	ANAPLASTIC LYMPHOMA KINASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402