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GENERAL
TITLE
STRUCTURE OF CYSTEINE-FREE HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH GLUCAGON AND SUBSTRATE-SELECTIVE MACROCYCLIC INHIBITOR 63
DATE LAST MODIFIED
29 May 2019
RELEASE
3 Apr 2019
OBSOLETE
CLASSIFICATION
HYDROLASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
3.18
RESOLUTION RANGE LOW
131.56
PUBMED ID
DOI
10.1038/S41589-019-0271-0
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P14735 | IDE | ESCHERICHIA COLI BL21(DE3) | HUMAN | ABETA-DEGRADING PROTEASE,INSULIN PROTEASE,INSULINA ... | Mutations | |
| P14735 | IDE | ESCHERICHIA COLI BL21(DE3) | HUMAN | ABETA-DEGRADING PROTEASE,INSULIN PROTEASE,INSULINA ... | Mutations | |
| P01275 | GCG | SACCHAROMYCES CEREVISIAE | HUMAN | -- | Mutations | |
| P01275 | GCG | SACCHAROMYCES CEREVISIAE | HUMAN | -- | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402