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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH AN ACETYLATED SIRT7 PEPTIDE (K272AC/K275AC)
DATE LAST MODIFIED
20 Feb 2019
RELEASE
28 Nov 2018
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.475
RESOLUTION RANGE LOW
51.805
PUBMED ID
DOI
10.1016/J.MOLCEL.2018.11.006
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60885 BRD4, HUNK1 ESCHERICHIA COLI BL21(DE3) HUMAN PROTEIN HUNK1 HUMAN
PROTEIN HUNK1
Mutations
O60885 BRD4, HUNK1 ESCHERICHIA COLI BL21(DE3) HUMAN PROTEIN HUNK1 HUMAN
PROTEIN HUNK1
Mutations
Q9NRC8 -- -- HUMAN REGULATORY PROTEIN SIR2 HOMOLOG 7,SIR2-LIKE PROTEIN 7TYR ADDED FOR UV DETECTION HUMAN
REGULATORY PROTEIN SIR2 HOMOLOG 7,SIR2-LIKE PROTEI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402