6GI6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6GI6_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE ACVR1 (ALK2) KINASE IN COMPLEX WITH A QUINAZOLINONE BASED ALK2 INHIBITOR WITH A 5-METHYL CORE.

DATE LAST MODIFIED

5 Sept 2018

RELEASE

23 May 2018

OBSOLETE

CLASSIFICATION

SIGNALING PROTEIN

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 32 2 1

RESOLUTION RANGE HIGH

1.98

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.8B00782

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P0CG48	ACVR1, ACVRLK2	SPODOPTERA FRUGIPERDA	HUMAN	ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402