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3D Structure View

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GENERAL
TITLE
CDK2/CYCLIN A2 IN COMPLEX WITH PYRAZOLO[4,3-D]PYRIMIDINE INHIBITOR LGR4455
DATE LAST MODIFIED
22 May 2019
RELEASE
1 May 2019
OBSOLETE
CLASSIFICATION
CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.15
RESOLUTION RANGE LOW
48
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B00189

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P24941 CDK2, CDKN2 ESCHERICHIA COLI HUMAN
CELL DIVISION PROTEIN KINASE 2,P33 PROTEIN KINASE
Mutations
P20248 CCNA2, CCN1, CCNA ESCHERICHIA COLI HUMAN
CYCLIN-A,CYCLIN A
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402