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GENERAL
TITLE
STRUCTURE OF THE KINASE DOMAIN OF HUMAN DDR1 IN COMPLEX WITH A POTENT AND SELECTIVE INHIBITOR OF DDR1 AND DDR2
DATE LAST MODIFIED
26 Sept 2018
RELEASE
8 Aug 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
30.7
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01045

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08345 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE SPODOPTERA FRUGIPERDA HUMAN EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIGEN-LIKEFAMILY MEMBER A,CELL ADHESION KINASE,DISCOIDIN RECEPTOR TYROSINEKINASE,HGK2,MAMMARY CARCINOMA KINASE 10,MCK-10,PROTEIN-TYROSINEKINASE 3A,PROTEIN-TYROSINE KINASE RTK-6,TRK E,TYROSINE KINASE DDR,TYROSINE-PROTEIN KINASE CAK HUMAN
EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIG ...
Mutations
Q08345 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE SPODOPTERA FRUGIPERDA HUMAN EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIGEN-LIKEFAMILY MEMBER A,CELL ADHESION KINASE,DISCOIDIN RECEPTOR TYROSINEKINASE,HGK2,MAMMARY CARCINOMA KINASE 10,MCK-10,PROTEIN-TYROSINEKINASE 3A,PROTEIN-TYROSINE KINASE RTK-6,TRK E,TYROSINE KINASE DDR,TYROSINE-PROTEIN KINASE CAK HUMAN
EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIG ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402