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GENERAL
TITLE
STRUCTURE OF DDB1-CRBN-POMALIDOMIDE COMPLEX BOUND TO IKZF1(ZF2)
DATE LAST MODIFIED
30 Oct 2019
RELEASE
7 Nov 2018
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.25
RESOLUTION RANGE LOW
39.85
PUBMED ID
DOI
10.1126/SCIENCE.AAT0572
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q16531 DDB1, XAP1 TRICHOPLUSIA NI CYPOVIRUS 15 HUMAN -- Mutations
Q96SW2 CRBN, AD-006 TRICHOPLUSIA NI HUMAN -- Mutations
Q13422 IKZF1, IK1, IKAROS, LYF1, ZNFN1A1 TRICHOPLUSIA NI HUMAN
IKAROS FAMILY ZINC FINGER PROTEIN 1,LYMPHOID TRANS ...
Mutations
Q16531 DDB1, XAP1 TRICHOPLUSIA NI CYPOVIRUS 15 HUMAN -- Mutations
Q96SW2 CRBN, AD-006 TRICHOPLUSIA NI HUMAN -- Mutations
Q13422 IKZF1, IK1, IKAROS, LYF1, ZNFN1A1 TRICHOPLUSIA NI HUMAN
IKAROS FAMILY ZINC FINGER PROTEIN 1,LYMPHOID TRANS ...
Mutations
Q16531 DDB1, XAP1 TRICHOPLUSIA NI CYPOVIRUS 15 HUMAN -- Mutations
Q96SW2 CRBN, AD-006 TRICHOPLUSIA NI HUMAN -- Mutations
Q13422 IKZF1, IK1, IKAROS, LYF1, ZNFN1A1 TRICHOPLUSIA NI HUMAN
IKAROS FAMILY ZINC FINGER PROTEIN 1,LYMPHOID TRANS ...
Mutations
Q16531 DDB1, XAP1 TRICHOPLUSIA NI CYPOVIRUS 15 HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402