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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE BRISC COMPLEX BOUND TO SHMT2
DATE LAST MODIFIED
29 Jul 2020
RELEASE
10 Jul 2019
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.9
RESOLUTION RANGE LOW
3.9
PUBMED ID
DOI
10.1016/J.MOLCEL.2019.06.002
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q15018 ABRAXAS2, ABRO1, FAM175B, KIAA0157 TRICHOPLUSIA NI HUMAN
ABRAXAS BROTHER PROTEIN 1,PROTEIN FAM175B
Mutations
P0A3R5 BRCC3, BRCC36, C6.1A, CXORF53 TRICHOPLUSIA NI HUMAN
BRCA1-A COMPLEX SUBUNIT BRCC36,BRCA1/BRCA2-CONTAIN ...
P0A3R5 BABAM2, BRCC45, BRE TRICHOPLUSIA NI HUMAN
BRCA1-A COMPLEX SUBUNIT BRE,BRCA1/BRCA2-CONTAINING ...
P04977 BABAM1, C19ORF62, MERIT40, NBA1, HSPC142 TRICHOPLUSIA NI HUMAN
MEDIATOR OF RAP80 INTERACTIONS AND TARGETING SUBUN ...
P04979 SHMT2 ESCHERICHIA COLI BL21(DE3) HUMAN
SHMT,GLYCINE HYDROXYMETHYLTRANSFERASE,SERINE METHY ...
Q15018 ABRAXAS2, ABRO1, FAM175B, KIAA0157 TRICHOPLUSIA NI HUMAN
ABRAXAS BROTHER PROTEIN 1,PROTEIN FAM175B
Mutations
P0A3R5 BRCC3, BRCC36, C6.1A, CXORF53 TRICHOPLUSIA NI HUMAN
BRCA1-A COMPLEX SUBUNIT BRCC36,BRCA1/BRCA2-CONTAIN ...
P0A3R5 BABAM2, BRCC45, BRE TRICHOPLUSIA NI HUMAN
BRCA1-A COMPLEX SUBUNIT BRE,BRCA1/BRCA2-CONTAINING ...
P04977 BABAM1, C19ORF62, MERIT40, NBA1, HSPC142 TRICHOPLUSIA NI HUMAN
MEDIATOR OF RAP80 INTERACTIONS AND TARGETING SUBUN ...
P04979 SHMT2 ESCHERICHIA COLI BL21(DE3) HUMAN
SHMT,GLYCINE HYDROXYMETHYLTRANSFERASE,SERINE METHY ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402