6HAX logo

6HAX

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF PROTAC 2 IN COMPLEX WITH THE BROMODOMAIN OF HUMAN SMARCA2 AND PVHL:ELONGINC:ELONGINB
DATE LAST MODIFIED
3 Jul 2019
RELEASE
12 Jun 2019
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.35
RESOLUTION RANGE LOW
34.41
PUBMED ID
DOI
10.1038/S41589-019-0294-6

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P51531 SMARCA2, BAF190B, BRM, SNF2A, SNF2L2 ESCHERICHIA COLI BL21(DE3) HUMAN
ATP-DEPENDENT HELICASE SMARCA2,BRG1-ASSOCIATED FAC ...
Mutations
P40337 VHL ESCHERICHIA COLI BL21(DE3) HUMAN
PROTEIN G7,PVHL
Mutations
Q15369 ELOC, TCEB1 ESCHERICHIA COLI BL21(DE3) HUMAN
ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
Q15370 ELOB, TCEB2 ESCHERICHIA COLI BL21(DE3) HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
P51531 SMARCA2, BAF190B, BRM, SNF2A, SNF2L2 ESCHERICHIA COLI BL21(DE3) HUMAN
ATP-DEPENDENT HELICASE SMARCA2,BRG1-ASSOCIATED FAC ...
Mutations
P40337 VHL ESCHERICHIA COLI BL21(DE3) HUMAN
PROTEIN G7,PVHL
Mutations
Q15369 ELOC, TCEB1 ESCHERICHIA COLI BL21(DE3) HUMAN
ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
Q15370 ELOB, TCEB2 ESCHERICHIA COLI BL21(DE3) HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402