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GENERAL
TITLE
PXR IN COMPLEX WITH P2X4 INHIBITOR COMPOUND 25
DATE LAST MODIFIED
8 Jan 2020
RELEASE
4 Dec 2019
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.22
RESOLUTION RANGE LOW
45.15
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01304
PDBe
6HTY
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| O75469 | NR1I2, PXR, NCOA1, BHLHE74, SRC1 | ESCHERICHIA COLI | HUMAN | ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPTOR PXR,PREGNANE X RECEPTOR,STEROID AND XENOBIOTIC RECEPTOR,SXR,NCOA-1,CLASSE BASIC HELIX-LOOP-HELIX PROTEIN 74,BHLHE74,PROTEIN HIN-2,RIP160,RENAL CARCINOMA ANTIGEN NY-REN-52,STEROID RECEPTOR COACTIVATOR 1,SRC-1ARTIFACT LINKER; SRC-1, RESIDUES 678-700 | HUMAN | ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ... | Mutations | |
| O75469 | NR1I2, PXR, NCOA1, BHLHE74, SRC1 | ESCHERICHIA COLI | HUMAN | ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPTOR PXR,PREGNANE X RECEPTOR,STEROID AND XENOBIOTIC RECEPTOR,SXR,NCOA-1,CLASSE BASIC HELIX-LOOP-HELIX PROTEIN 74,BHLHE74,PROTEIN HIN-2,RIP160,RENAL CARCINOMA ANTIGEN NY-REN-52,STEROID RECEPTOR COACTIVATOR 1,SRC-1ARTIFACT LINKER; SRC-1, RESIDUES 678-700 | HUMAN | ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402