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GENERAL
TITLE
CRYOEM STRUCTURE OF HUMAN FULL-LENGTH HETEROMERIC ALPHA1BETA3GAMMA2L GABA(A)R IN COMPLEX WITH ALPRAZOLAM (XANAX), GABA AND MEGABODY MB38.
DATE LAST MODIFIED
30 Mar 2022
RELEASE
2 Jan 2019
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.26
RESOLUTION RANGE LOW
3.26
PUBMED ID
DOI
10.1038/S41586-018-0832-5
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P14867 | GABRA1 | HOMO SAPIENS | BOVINE, HUMAN | GABA(A) RECEPTOR SUBUNIT ALPHA-1,GABA(A) RECEPTOR ... | ||
| P14174 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | ||
| P14174 | GABRG2 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT GAMMA-2 | ||
| P14867 | GABRA1 | HOMO SAPIENS | BOVINE, HUMAN | GABA(A) RECEPTOR SUBUNIT ALPHA-1,GABA(A) RECEPTOR ... | ||
| Q16611 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | ||
| P14174 | -- | ESCHERICHIA COLI | LAMA GLAMA | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402