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GENERAL
TITLE
CRYSTAL STRUCTURE OF EPCAM IN COMPLEX WITH SCFV
DATE LAST MODIFIED
11 Mar 2020
RELEASE
13 Mar 2019
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.35
RESOLUTION RANGE LOW
28.7
PUBMED ID
DOI
10.1073/PNAS.1819085116
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
-- HOMO SAPIENS HUMAN -- HUMAN --
-- HOMO SAPIENS HUMAN -- HUMAN --
P16422 EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1 HOMO SAPIENS HUMAN EP-CAM,ADENOCARCINOMA-ASSOCIATED ANTIGEN,CELL SURFACEGLYCOPROTEIN TROP-1,EPITHELIAL CELL SURFACE ANTIGEN,EPITHELIALGLYCOPROTEIN,EGP,EPITHELIAL GLYCOPROTEIN 314,HEGP314,KS 1/4 ANTIGEN,KSA,MAJOR GASTROINTESTINAL TUMOR-ASSOCIATED PROTEIN GA733-2,TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 1MODIFICATION HUMAN
EP-CAM,ADENOCARCINOMA-ASSOCIATED ANTIGEN,CELL SURF ...
Mutations
P16422 EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1 HOMO SAPIENS HUMAN EP-CAM,ADENOCARCINOMA-ASSOCIATED ANTIGEN,CELL SURFACEGLYCOPROTEIN TROP-1,EPITHELIAL CELL SURFACE ANTIGEN,EPITHELIALGLYCOPROTEIN,EGP,EPITHELIAL GLYCOPROTEIN 314,HEGP314,KS 1/4 ANTIGEN,KSA,MAJOR GASTROINTESTINAL TUMOR-ASSOCIATED PROTEIN GA733-2,TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 1MODIFICATION HUMAN
EP-CAM,ADENOCARCINOMA-ASSOCIATED ANTIGEN,CELL SURF ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402