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GENERAL
TITLE
CRYSTAL STRUCTURE OF PARTIALLY PHOSPHORYLATED RET V804M TYROSINE KINASE DOMAIN COMPLEXED WITH PDD00018412
DATE LAST MODIFIED
22 Apr 2020
RELEASE
11 Mar 2020
OBSOLETE
CLASSIFICATION
ONCOPROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
45.89
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.9B00615

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P07949 RET, CDHF12, CDHR16, PTC, RET51 HOMO SAPIENS HUMAN CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET HUMAN
CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
Mutations
P07949 RET, CDHF12, CDHR16, PTC, RET51 HOMO SAPIENS HUMAN CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET HUMAN
CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402