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GENERAL
TITLE
CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A NOTCH FRAGMENT
DATE LAST MODIFIED
29 Jul 2020
RELEASE
26 Dec 2018
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.7
RESOLUTION RANGE LOW
2.7
PUBMED ID
DOI
10.1038/S41586-018-0813-8
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q92542 | NCSTN | HOMO SAPIENS | HUMAN | -- | Mutations | |
| P49768 | PS1 | HOMO SAPIENS | HUMAN | PS-1 | Mutations | |
| Q96BI3 | APH1A | HOMO SAPIENS | HUMAN | APH-1A | Mutations | |
| Q9NZ42 | PEN2 | HOMO SAPIENS | HUMAN | PRESENILIN ENHANCER PROTEIN 2 | Mutations | |
| -- | HOMO SAPIENS | HOMO SAPIENS | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402