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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE HUMAN THROMBOXANE A2 RECEPTOR BOUND TO RAMATROBAN
DATE LAST MODIFIED
26 Dec 2018
RELEASE
19 Dec 2018
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/S41589-018-0170-9
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P00268 CYBC, TBXA2R SPODOPTERA FRUGIPERDA HUMAN CYTOCHROME B-562,TXA2-R,PROSTANOID TP RECEPTOR,RD,TXA2-R,PROSTANOID TP RECEPTORINTRODUCING A BRIL FUSION PROTEIN AT THE N TERMINUS OF THE RECEPTORAND A RUBREDOXIN FUSION PROTEIN IN THE THIRD INTRACELLULAR LOOP OFTHE RECEPTOR. THE RESIDUES FROM BRIL WERE NUMBERED WITH 1001-1106 ANDTHE RESIDUES FROM RUBREDOXIN WERE NUMBERED WITH 2001 TO 2054, WITH2001 AND 2054 COVALENTLY LINKED TO RESIDUES 228 AND 237 OF THERECEPTOR, RESPECTIVELY. HUMAN
CYTOCHROME B-562,TXA2-R,PROSTANOID TP RECEPTOR,RD, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402