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GENERAL
TITLE
CRYSTAL STRUCTURE OF FXR IN COMPLEX WITH AGONIST XJ034
DATE LAST MODIFIED
10 Jun 2020
RELEASE
27 Nov 2019
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JCIM.9B01030
PDBe
6ITM
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| Q96RI1 | NR1H4, BAR, FXR, HRR1, RIP14 | ESCHERICHIA COLI BL21(DE3) | HUMAN | FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR HRR-1,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP H MEMBER 4,RETINOID X RECEPTOR-INTERACTING PROTEIN 14,RXR-INTERACTING PROTEIN 14 | HUMAN | FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ... | Mutations | |
| Q15788 | -- | -- | HUMAN | SRC-1 HD3 | HUMAN | SRC-1 HD3 | Mutations | |
| Q96RI1 | NR1H4, BAR, FXR, HRR1, RIP14 | ESCHERICHIA COLI BL21(DE3) | HUMAN | FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR HRR-1,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP H MEMBER 4,RETINOID X RECEPTOR-INTERACTING PROTEIN 14,RXR-INTERACTING PROTEIN 14 | HUMAN | FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ... | Mutations | |
| Q15788 | -- | -- | HUMAN | SRC-1 HD3 | HUMAN | SRC-1 HD3 | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402