6IW7

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6IW7_1

Bioassembly 6IW7_2

Bioassembly 6IW7_3

Bioassembly 6IW7_4

Bioassembly 6IW7_5

Bioassembly 6IW7_6

Bioassembly 6IW7_7

Chain 6IW7_A

Chain 6IW7_B

Chain 6IW7_C

Chain 6IW7_D

Chain 6IW7_E

Chain 6IW7_F

Chain 6IW7_G

Chain 6IW7_H

Chain 6IW7_I

Chain 6IW7_J

Chain 6IW7_K

Chain 6IW7_L

Chain 6IW7_M

Chain 6IW7_N

Chain 6IW7_O

Chain 6IW7_P

Chain 6IW7_Q

Chain 6IW7_R

Chain 6IW7_T

Chain 6IW7_U

Chain 6IW7_V

Chain 6IW7_W

Chain 6IW7_X

Chain 6IW7_Z

Chain 6IW7_a

Chain 6IW7_b

Chain 6IW7_d

Chain 6IW7_e

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GENERAL

TITLE

STRUCTURAL INSIGHTS INTO MYCOBACTERIUM TUBERCULOSIS CLPP1P2 INHIBITION BY CEDIRANIB: IMPLICATIONS FOR DEVELOPING ANTIMICROBIAL AGENTS TARGETING CLP PROTEASE

DATE LAST MODIFIED

29 Apr 2020

RELEASE

1 Jan 2020

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.69

RESOLUTION RANGE LOW

PUBMED ID

DOI

PDBe

6IW7

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P0A017	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2
P35568	CLPP1, CLPP, MT2536	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 1
Q6QLM7	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2
P36979	CLPP1, CLPP, MT2536	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 1
Q9KEI9	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2
P77218	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2
Q06124	CLPP1, CLPP, MT2536	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 1
O60282	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2
P9WPC4	CLPP1, CLPP, MT2536	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 1	Mutations
O60282	CLPP2, MT2535	ESCHERICHIA COLI BL21(DE3)	MYCOBACTERIUM TUBERCULOSIS CDC1551	ENDOPEPTIDASE CLP 2

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402