6NEC

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6NEC_A

Chain 6NEC_C

Spin

Focus

Transparency

GENERAL

TITLE

STRUCTURE OF RET PROTEIN TYROSINE KINASE DOMAIN IN COMPLEX WITH NINTEDANIB

DATE LAST MODIFIED

18 Dec 2019

RELEASE

5 Jun 2019

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.87

RESOLUTION RANGE LOW

78.6

PUBMED ID

DOI

10.1074/JBC.RA119.007682

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P00800	RET, CDHF12, CDHR16, PTC, RET51	SPODOPTERA FRUGIPERDA	HUMAN	CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET
	P07949	RET, CDHF12, CDHR16, PTC, RET51	SPODOPTERA FRUGIPERDA	HUMAN	CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402