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GENERAL
TITLE
CRYSTAL STRUCTURE OF HPK1 KINASE DOMAIN T165E,S171E PHOSPHOMIMETIC MUTANT IN COMPLEX WITH SUNITINIB IN THE INACTIVE STATE.
DATE LAST MODIFIED
26 Jun 2019
RELEASE
1 May 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.026
RESOLUTION RANGE LOW
60.176
PUBMED ID
DOI
10.1074/JBC.AC119.007466
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q92918 MAP4K1, HPK1 SPODOPTERA FRUGIPERDA HUMAN
HEMATOPOIETIC PROGENITOR KINASE,MAPK/ERK KINASE KI ...
Mutations
Q92918 MAP4K1, HPK1 SPODOPTERA FRUGIPERDA HUMAN
HEMATOPOIETIC PROGENITOR KINASE,MAPK/ERK KINASE KI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402