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GENERAL
TITLE
THE CO-CRYSTAL STRUCTURE OF BRAF(V600E) WITH PONATINIB
DATE LAST MODIFIED
-
RELEASE
23 Sept 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 2 2
RESOLUTION RANGE HIGH
2.105
RESOLUTION RANGE LOW
118.839
PUBMED ID
DOI
10.1038/S41467-020-18123-2

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P15056 BRAF, BRAF1, RAFB1 ESCHERICHIA COLI HUMAN
PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402