6P3D

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6P3D_1

Chain 6P3D_A

Spin

Focus

Transparency

GENERAL

TITLE

THE CO-CRYSTAL STRUCTURE OF BRAF(V600E) WITH PONATINIB

DATE LAST MODIFIED

RELEASE

23 Sept 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 43 2 2

RESOLUTION RANGE HIGH

2.105

RESOLUTION RANGE LOW

118.839

PUBMED ID

DOI

10.1038/S41467-020-18123-2

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P29283	BRAF, BRAF1, RAFB1	ESCHERICHIA COLI	HUMAN	PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402