6P8Q

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6P8Q_1

Bioassembly 6P8Q_2

Chain 6P8Q_A

Chain 6P8Q_B

Chain 6P8Q_C

Chain 6P8Q_D

Spin

Focus

Transparency

GENERAL

TITLE

EGFR IN COMPLEX WITH A DIHYDRODIBENZODIAZEPINONE ALLOSTERIC INHIBITOR.

DATE LAST MODIFIED

RELEASE

18 Dec 2019

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACSMEDCHEMLETT.9B00381

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P00533	EGFR, ERBB, ERBB1, HER1	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ...	Mutations
P00533	EGFR, ERBB, ERBB1, HER1	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ...	Mutations
P00533	EGFR, ERBB, ERBB1, HER1	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ...	Mutations
P00533	EGFR, ERBB, ERBB1, HER1	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402