6P8Y logo
TITLE
CRYSTAL STRUCTURE OF HUMAN KRAS G12C COVALENTLY BOUND TO AN ACRYLOYLAZETIDINE ACETAMIDE INHIBITOR.
EXPRESSION SYSTEM(S)
ESCHERICHIA COLI BL21(DE3) ,
EXPERIMENT TYPE
X-RAY DIFFRACTION
ORGANISM(S)
HOMO SAPIENS ,
CLASSIFICATION
SIGNALING PROTEIN/INHIBITOR
SPACE GROUP:
P 1 21 1
RESOLUTION RANGE HIGH:
2.3
RESOLUTION RANGE LOW:
30
DOI:
10.1021/ACSMEDCHEMLETT.9B00258
EM DATA RESOURCE:
--
DATE DEPOSITED:
2019-06-08 00:00:00
DATE RELEASED:
2019-08-28 00:00:00
DATE REVISED:
2019-10-02 00:00:00
BIOLOGICAL ASSEMBLY:
--
6P8Y logo

3D Structure - 6P8Y

3D Viewer

6P8Y_B
Loading...

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonyms
6P8Y_B P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI BL21(DE3) HUMAN K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
6P8Y_A P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI BL21(DE3) HUMAN K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS