6Q2T

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6Q2T_A

Chain 6Q2T_B

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GENERAL

TITLE

HUMAN STEROL 14A-DEMETHYLASE (CYP51) IN COMPLEX WITH THE FUNCTIONALLY IRREVERSIBLE INHIBITOR (R)-N-(1-(3-CHLORO-4'-FLUORO-[1,1'-BIPHENYL]- 4-YL)-2-(1H-IMIDAZOL-1-YL)ETHYL)-4-(5-(3-FLUORO-5-(5-FLUOROPYRIMIDIN- 4-YL)PHENYL)-1,3,4-OXADIAZOL-2-YL)BENZAMIDE

DATE LAST MODIFIED

1 Jan 2020

RELEASE

13 Nov 2019

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 4

RESOLUTION RANGE HIGH

2.8

RESOLUTION RANGE LOW

94.35

PUBMED ID

31663733

DOI

10.1021/ACS.JMEDCHEM.9B01485

PDBe

6Q2T

LIGANDS

, 2693499 , 2956397

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P0DTD1	CYP51A1, CYP51	ESCHERICHIA COLI	HUMAN	LDM, CYPLI, CYTOCHROME P450 51A1, CYTOCHROME P450- ...
	P0DTD1	CYP51A1, CYP51	ESCHERICHIA COLI	HUMAN	LDM, CYPLI, CYTOCHROME P450 51A1, CYTOCHROME P450- ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402