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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE CSF1R KINASE DOMAIN WITH A DIHYDROPURINONE INHIBITOR (COMPOUND 4)
DATE LAST MODIFIED
22 Apr 2020
RELEASE
1 Jan 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
H 3
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
50.59
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01684

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07333 CSF1R, FMS SPODOPTERA FRUGIPERDA HUMAN
CSF-1 RECEPTOR,M-CSF-R,PROTO-ONCOGENE C-FMS
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402