6TE6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6TE6_A

Chain 6TE6_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF DOT1L IN COMPLEX WITH AN INHIBITOR (COMPOUND 3).

DATE LAST MODIFIED

11 Mar 2020

RELEASE

11 Dec 2019

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 63

RESOLUTION RANGE HIGH

1.98

RESOLUTION RANGE LOW

45.77

PUBMED ID

DOI

10.1021/ACSMEDCHEMLETT.9B00452

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q8TEK3	DOT1L, KIAA1814, KMT4	ESCHERICHIA COLI	HUMAN	DOT1-LIKE PROTEIN,HISTONE H3-K79 METHYLTRANSFERASE ...	Mutations
	Q8TEK3	DOT1L, KIAA1814, KMT4	ESCHERICHIA COLI	HUMAN	DOT1-LIKE PROTEIN,HISTONE H3-K79 METHYLTRANSFERASE ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402