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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH THE INHIBITOR ZL0590
DATE LAST MODIFIED
19 Jan 2022
RELEASE
19 Aug 2020
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.429
RESOLUTION RANGE LOW
33.954
PUBMED ID
-
DOI
10.1021/ACS.JMEDCHEM.1C01851
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O60885 BRD4, HUNK1 ESCHERICHIA COLI BL21(DE3) HUMAN
PROTEIN HUNK1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402