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GENERAL
TITLE
CRYSTAL STRUCTURE OF N-(4-((4-METHOXY-N-(2,2,2-TRIFLUOROETHYL)PHENYL) SULFONAMIDO)ISOQUINOLIN-1-YL)-N-((4-METHOXYPHENYL)SULFONYL)GLYCINE BOUND TO HUMAN KEAP1 KELCH DOMAIN
DATE LAST MODIFIED
8 Jul 2020
RELEASE
18 Dec 2019
OBSOLETE
CLASSIFICATION
PROTEIN BINDING
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
1.96
RESOLUTION RANGE LOW
19.87
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01074
PDBe
6UF0
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P9WK11 | KEAP1, INRF2, KIAA0132, KLHL19 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KELCH-LIKE PRO ... | ||
| C1ITJ8 | KEAP1, INRF2, KIAA0132, KLHL19 | ESCHERICHIA COLI BL21(DE3) | HUMAN | CYTOSOLIC INHIBITOR OF NRF2, INRF2, KELCH-LIKE PRO ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402