6V32

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6V32_A

Chain 6V32_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE BRAF:MEK1 KINASES IN COMPLEX WITH AMPPNP AND SELUMETINIB

DATE LAST MODIFIED

RELEASE

2 Dec 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 31 2 1

RESOLUTION RANGE HIGH

3.19

RESOLUTION RANGE LOW

43.44

PUBMED ID

DOI

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P15056	BRAF, BRAF1, RAFB1	SPODOPTERA FRUGIPERDA	HUMAN	PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
	Q02750	MAP2K1, MEK1, PRKMK1	SPODOPTERA FRUGIPERDA	HUMAN	MKK1,ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1,MEK ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402