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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR IN COMPLEX WITH G PROTEIN, GLP-1 PEPTIDE AND A POSITIVE ALLOSTERIC MODULATOR
DATE LAST MODIFIED
30 Sept 2020
RELEASE
22 Jul 2020
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
3.3
PUBMED ID
DOI
10.1038/S41589-020-0589-7
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| O25119 | GNAS, GNAS1, GSP | SPODOPTERA FRUGIPERDA | HUMAN | ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN | ||
| O25119 | GNB1 | SPODOPTERA FRUGIPERDA | HUMAN | TRANSDUCIN BETA CHAIN 1 | ||
| P00947 | GNG2 | SPODOPTERA FRUGIPERDA | HUMAN | G GAMMA-I | ||
| Q8IU60 | -- | ESCHERICHIA COLI | LLAMA | -- | ||
| P00947 | -- | -- | HUMAN | -- | ||
| P43220 | -- | -- | HUMAN | GLP-1R | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402