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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR IN COMPLEX WITH G PROTEIN, GLP-1 PEPTIDE AND A POSITIVE ALLOSTERIC MODULATOR
DATE LAST MODIFIED
30 Sept 2020
RELEASE
22 Jul 2020
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
3.3
PUBMED ID
DOI
10.1038/S41589-020-0589-7
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P63092 GNAS, GNAS1, GSP SPODOPTERA FRUGIPERDA HUMAN ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN HUMAN
ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN
Mutations
P62873 GNB1 SPODOPTERA FRUGIPERDA HUMAN TRANSDUCIN BETA CHAIN 1 HUMAN
TRANSDUCIN BETA CHAIN 1
Mutations
P59768 GNG2 SPODOPTERA FRUGIPERDA HUMAN G GAMMA-I HUMAN
G GAMMA-I
Mutations
-- ESCHERICHIA COLI LLAMA -- LLAMA --
P01275 -- -- HUMAN -- HUMAN -- Mutations
P43220 -- -- HUMAN GLP-1R HUMAN
GLP-1R
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402