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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN TRANSCRIPTION FACTOR ERG, HUMAN RUNX2 BOUND TO CORE BINDING FACTOR BETA (CBFB), AND MITHRAMYCIN, IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC
DATE LAST MODIFIED
19 May 2021
RELEASE
25 Nov 2020
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 62 2 2
RESOLUTION RANGE HIGH
4.3
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.STR.2020.11.012
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P11308 ERG ESCHERICHIA COLI BL21(DE3) HUMAN TRANSFORMING PROTEIN ERGAFFINITY TAG AFTER ITS CLEAVAGE. HUMAN
TRANSFORMING PROTEIN ERGAFFINITY TAG AFTER ITS CLE ...
Mutations
-- -- HUMAN -- HUMAN --
-- -- HUMAN -- HUMAN --
Q13950 RUNX2, AML3, CBFA1, OSF2, PEBP2A ESCHERICHIA COLI BL21(DE3) HUMAN ACUTE MYELOID LEUKEMIA 3 PROTEIN,CORE-BINDING FACTOR SUBUNITALPHA-1,CBF-ALPHA-1,ONCOGENE AML-3,OSTEOBLAST-SPECIFIC TRANSCRIPTIONFACTOR 2,OSF-2,POLYOMAVIRUS ENHANCER-BINDING PROTEIN 2 ALPHA ASUBUNIT,PEBP2-ALPHA A,SL3-3 ENHANCER FACTOR 1 ALPHA A SUBUNIT,SL3/AKVCORE-BINDING FACTOR ALPHA A SUBUNIT HUMAN
ACUTE MYELOID LEUKEMIA 3 PROTEIN,CORE-BINDING FACT ...
Mutations
Q13951 CBFB ESCHERICHIA COLI BL21(DE3) HUMAN CBF-BETA,POLYOMAVIRUS ENHANCER-BINDING PROTEIN 2 BETASUBUNIT,PEBP2-BETA,SL3-3 ENHANCER FACTOR 1 SUBUNIT BETA,SL3/AKV CORE-BINDING FACTOR BETA SUBUNITTAG. HUMAN
CBF-BETA,POLYOMAVIRUS ENHANCER-BINDING PROTEIN 2 B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402