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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN TRANSCRIPTION FACTOR ERG, HUMAN RUNX2 BOUND TO CORE BINDING FACTOR BETA (CBFB), AND MITHRAMYCIN, IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC
DATE LAST MODIFIED
19 May 2021
RELEASE
25 Nov 2020
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 62 2 2
RESOLUTION RANGE HIGH
4.3
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.STR.2020.11.012
PDBe
6VGG
LIGANDS
2694373 ,
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P11308 | ERG | ESCHERICHIA COLI BL21(DE3) | HUMAN | TRANSFORMING PROTEIN ERGAFFINITY TAG AFTER ITS CLE ... | Mutations | |
| -- | -- | HUMAN | -- | |||
| -- | -- | HUMAN | -- | |||
| Q13950 | RUNX2, AML3, CBFA1, OSF2, PEBP2A | ESCHERICHIA COLI BL21(DE3) | HUMAN | ACUTE MYELOID LEUKEMIA 3 PROTEIN,CORE-BINDING FACT ... | Mutations | |
| Q13951 | CBFB | ESCHERICHIA COLI BL21(DE3) | HUMAN | CBF-BETA,POLYOMAVIRUS ENHANCER-BINDING PROTEIN 2 B ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402