6VGL

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6VGL_A

Chain 6VGL_B

Chain 6VGL_C

Chain 6VGL_D

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GENERAL

TITLE

JAK2 JH1 IN COMPLEX WITH RUXOLITINIB

DATE LAST MODIFIED

10 Mar 2021

RELEASE

13 Jan 2021

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

52.82

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.0C01952

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P37064	JAK2	HOMO SAPIENS	HUMAN	JANUS KINASE 2,JAK-2
O60674	JAK2	HOMO SAPIENS	HUMAN	JANUS KINASE 2,JAK-2	Mutations
O60674	JAK2	HOMO SAPIENS	HUMAN	JANUS KINASE 2,JAK-2	Mutations
P19793	JAK2	HOMO SAPIENS	HUMAN	JANUS KINASE 2,JAK-2

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402