6VHG

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6VHG_A

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GENERAL

TITLE

CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN COMPLEXED WITH A PYRAZOLO[1,5-A]PYRIMIDINE INHIBITOR

DATE LAST MODIFIED

29 Apr 2020

RELEASE

26 Feb 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 63 2 2

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACSMEDCHEMLETT.0C00015

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P0A6F5	RET, CDHF12, CDHR16, PTC, RET51	SPODOPTERA FRUGIPERDA	HUMAN	CADHERIN FAMILY MEMBER 12,PROTO-ONCOGENE C-RET

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402