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GENERAL
TITLE
CRYSTAL STRUCTURE OF PI3K-ALPHA RAS BINDING DOMAIN (RBD)
DATE LAST MODIFIED
10 Mar 2021
RELEASE
3 Feb 2021
OBSOLETE
CLASSIFICATION
ONCOPROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.31
RESOLUTION RANGE LOW
35.09
PUBMED ID
DOI
10.1016/J.JMB.2021.166838
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P42336 PIK3CA ESCHERICHIA COLI HUMAN PTDINS-3-KINASE SUBUNIT ALPHA,PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT ALPHA,P110ALPHA,PHOSPHOINOSITIDE-3-KINASE CATALYTIC ALPHA POLYPEPTIDE,SERINE/THREONINE PROTEIN KINASE PIK3CA HUMAN
PTDINS-3-KINASE SUBUNIT ALPHA,PHOSPHATIDYLINOSITOL ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402