6W0Y

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6W0Y_1

Chain 6W0Y_A

Chain 6W0Y_B

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GENERAL

TITLE

STRUCTURE OF KHK IN COMPLEX WITH COMPOUND 6 (2-[(1~{R},5~{S})-3-[5- CYANO-6-[(2~{S},3~{R})-2-METHYL-3-OXIDANYL-AZETIDIN-1-YL]-4- (TRIFLUOROMETHYL)PYRIDIN-2-YL]-3-AZABICYCLO[3.1.0]HEXAN-6-YL]ETHANOIC ACID)

DATE LAST MODIFIED

9 Dec 2020

RELEASE

23 Sept 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.54

RESOLUTION RANGE LOW

83.56

PUBMED ID

32910646

DOI

10.1021/ACS.JMEDCHEM.0C00944

PDBe

6W0Y

LIGANDS

, 2730972

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P50053	KHK	ESCHERICHIA COLI	HUMAN	HEPATIC FRUCTOKINASE	Mutations
	P50053	KHK	ESCHERICHIA COLI	HUMAN	HEPATIC FRUCTOKINASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402