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GENERAL
TITLE
A CRYSTAL STRUCTURE OF EGFR(T790M/V948R) IN COMPLEX WITH LN3754
DATE LAST MODIFIED
9 Feb 2022
RELEASE
31 Mar 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
85.59
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C00848
PDBe
6WAK
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P00388 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | ||
| P00533 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | Mutations | |
| P06202 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | ||
| P00388 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402