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GENERAL
TITLE
DUPILUMAB FAB WITH CRYSTAL KAPPA DESIGN COMPLEXED WITH HUMAN IL-4 RECEPTOR
DATE LAST MODIFIED
23 Sept 2020
RELEASE
16 Sept 2020
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
2.82
RESOLUTION RANGE LOW
103.11
PUBMED ID
DOI
10.1371/JOURNAL.PONE.0232311
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
-- CRICETULUS GRISEUS HUMAN -- HUMAN --
A0A075B6P5 -- CRICETULUS GRISEUS HUMAN -- HUMAN --
P24394 IL4R, IL4RA, 582J2.1 CRICETULUS GRISEUS HUMAN IL-4RA HUMAN
IL-4RA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402