6WR0

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6WR0_A

Chain 6WR0_B

Chain 6WR0_C

Chain 6WR0_D

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GENERAL

TITLE

HUMAN STEROIDOGENIC CYTOCHROME P450 17A1 WITH 3-KETO-DELTA4- ABIRATERONE ANALOG

DATE LAST MODIFIED

RELEASE

5 May 2021

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.7

RESOLUTION RANGE LOW

39.81

PUBMED ID

DOI

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonyms	Actions
P05093	CYP17A1, CYP17, S17AH	ESCHERICHIA COLI	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTOCHROMEP450 17A1,CYTOCHROME P450-C17,CYTOCHROME P450C17,STEROID 17-ALPHA-MONOOXYGENASE	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTO ...	Mutations
P05093	CYP17A1, CYP17, S17AH	ESCHERICHIA COLI	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTOCHROMEP450 17A1,CYTOCHROME P450-C17,CYTOCHROME P450C17,STEROID 17-ALPHA-MONOOXYGENASE	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTO ...	Mutations
P05093	CYP17A1, CYP17, S17AH	ESCHERICHIA COLI	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTOCHROMEP450 17A1,CYTOCHROME P450-C17,CYTOCHROME P450C17,STEROID 17-ALPHA-MONOOXYGENASE	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTO ...	Mutations
P05093	CYP17A1, CYP17, S17AH	ESCHERICHIA COLI	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTOCHROMEP450 17A1,CYTOCHROME P450-C17,CYTOCHROME P450C17,STEROID 17-ALPHA-MONOOXYGENASE	HUMAN	17-ALPHA-HYDROXYPROGESTERONE ALDOLASE,CYPXVII,CYTO ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402