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GENERAL
TITLE
MOLECULAR MECHANISM AND STRUCTURAL BASIS OF SMALL-MOLECULE MODULATION OF ACID-SENSING ION CHANNEL 1 (ASIC1)
DATE LAST MODIFIED
14 Jul 2021
RELEASE
30 Dec 2020
OBSOLETE
CLASSIFICATION
TRANSPORT PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3
RESOLUTION RANGE LOW
35.845
PUBMED ID
DOI
10.1038/S42003-021-01678-1
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q1XA76 ASIC1, ACCN2 SPODOPTERA FRUGIPERDA CHICKEN ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONAL CHICKEN
ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONA ...
Mutations
Q1XA76 ASIC1, ACCN2 SPODOPTERA FRUGIPERDA CHICKEN ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONAL CHICKEN
ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONA ...
Mutations
Q1XA76 ASIC1, ACCN2 SPODOPTERA FRUGIPERDA CHICKEN ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONAL CHICKEN
ASIC1,AMILORIDE-SENSITIVE CATION CHANNEL 2,NEURONA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402