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GENERAL
TITLE
CRYSTAL STRUCTURE OF KRAS-Q61R (GMPPNP-BOUND) IN COMPLEX WITH RAS- BINDING DOMAIN (RBD) AND CYSTEINE-RICH DOMAIN (CRD) OF RAF1/CRAF
DATE LAST MODIFIED
14 Jul 2021
RELEASE
13 Jan 2021
OBSOLETE
CLASSIFICATION
ONCOPROTEIN/TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 6 2 2
RESOLUTION RANGE HIGH
2.7
RESOLUTION RANGE LOW
48.32
PUBMED ID
DOI
10.1038/S41467-021-21422-X

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI HUMAN K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS HUMAN
K-RAS 2,KI-RAS,C-K-RAS,C-KI-RAS
Mutations
P04049 RAF1, RAF ESCHERICHIA COLI HUMAN PROTO-ONCOGENE C-RAF,CRAF,RAF-1 HUMAN
PROTO-ONCOGENE C-RAF,CRAF,RAF-1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402