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GENERAL
TITLE
CRYSTAL STRUCTURE OF KPT-185 BOUND TO CRM1 (537-DLTVK-541 TO GLCEQ)
DATE LAST MODIFIED
-
RELEASE
27 Jan 2021
OBSOLETE
CLASSIFICATION
PROTEIN TRANSPORT
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1186/S13045-021-01032-2

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P62826 RAN, ARA24, OK/SW-CL.81 ESCHERICHIA COLI BL21(DE3) HUMAN ANDROGEN RECEPTOR-ASSOCIATED PROTEIN 24,GTPASE RAN,RAS-LIKEPROTEIN TC4,RAS-RELATED NUCLEAR PROTEIN HUMAN
ANDROGEN RECEPTOR-ASSOCIATED PROTEIN 24,GTPASE RAN ...
Mutations
P41920 YRB1, CST20, HTN1, SFO1, YDR002W, YD8119.08 ESCHERICHIA COLI BL21(DE3) BAKER'S YEAST CHROMOSOME STABILITY PROTEIN 20,PERINUCLEAR ARRAY-LOCALIZEDPROTEIN,RAN-BINDING PROTEIN 1,RANBP1 BAKER'S YEAST
CHROMOSOME STABILITY PROTEIN 20,PERINUCLEAR ARRAY- ...
Mutations
P30822 CRM1, KAP124, XPO1, YGR218W, G8514 ESCHERICHIA COLI BL21(DE3) BAKER'S YEAST CHROMOSOME REGION MAINTENANCE PROTEIN 1,KARYOPHERIN-124 BAKER'S YEAST
CHROMOSOME REGION MAINTENANCE PROTEIN 1,KARYOPHERI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402