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GENERAL
TITLE
CEREBLON IN COMPLEX WITH DDB1, CC-90009, AND GSPT1
DATE LAST MODIFIED
24 Feb 2021
RELEASE
2 Dec 2020
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 2 1
RESOLUTION RANGE HIGH
3.64
RESOLUTION RANGE LOW
74.45
PUBMED ID
DOI
10.1182/BLOOD.2020008676
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P15170 GSPT1, ERF3A ESCHERICHIA COLI HUMAN ERF3A,G1 TO S PHASE TRANSITION PROTEIN 1 HOMOLOG HUMAN
ERF3A,G1 TO S PHASE TRANSITION PROTEIN 1 HOMOLOG
Mutations
Q16531 DDB1, XAP1 SPODOPTERA FRUGIPERDA HUMAN DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1,HBV X-ASSOCIATED PROTEIN 1,UV-DAMAGEDDNA-BINDING FACTOR,UV-DAMAGED DNA-BINDING PROTEIN 1,XPE-BINDINGFACTOR,XERODERMA PIGMENTOSUM GROUP E-COMPLEMENTING PROTEIN HUMAN
DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DAMA ...
Mutations
Q96SW2 CRBN, AD-006 SPODOPTERA FRUGIPERDA HUMAN -- HUMAN -- Mutations
P15170 GSPT1, ERF3A ESCHERICHIA COLI HUMAN ERF3A,G1 TO S PHASE TRANSITION PROTEIN 1 HOMOLOG HUMAN
ERF3A,G1 TO S PHASE TRANSITION PROTEIN 1 HOMOLOG
Mutations
Q16531 DDB1, XAP1 SPODOPTERA FRUGIPERDA HUMAN DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1,HBV X-ASSOCIATED PROTEIN 1,UV-DAMAGEDDNA-BINDING FACTOR,UV-DAMAGED DNA-BINDING PROTEIN 1,XPE-BINDINGFACTOR,XERODERMA PIGMENTOSUM GROUP E-COMPLEMENTING PROTEIN HUMAN
DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DAMA ...
Mutations
Q96SW2 CRBN, AD-006 SPODOPTERA FRUGIPERDA HUMAN -- HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402