6XOX logo

6XOX

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYO-EM OF HUMAN GLP-1R BOUND TO NON-PEPTIDE AGONIST LY3502970
DATE LAST MODIFIED
9 Dec 2020
RELEASE
18 Nov 2020
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.1
RESOLUTION RANGE LOW
3.1
PUBMED ID
DOI
10.1073/PNAS.2014879117
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P63092 GNAS, GNAS, GNAS1 TRICHOPLUSIA NI HUMAN ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN,EXTRA LARGEALPHAS PROTEIN,XLALPHAS HUMAN
ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN,EXTR ...
Mutations
P62873 GNB1 TRICHOPLUSIA NI HUMAN TRANSDUCIN BETA CHAIN 1 HUMAN
TRANSDUCIN BETA CHAIN 1
Mutations
-- SPODOPTERA FRUGIPERDA MOUSE -- MOUSE --
P59768 GNG2 TRICHOPLUSIA NI HUMAN G GAMMA-I HUMAN
G GAMMA-I
Mutations
-- ESCHERICHIA COLI LAMA GLAMA -- LAMA GLAMA --
P43220 GLP1R SPODOPTERA FRUGIPERDA HUMAN GLP-1R HUMAN
GLP-1R
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402