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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PI3K-GAMMA IN COMPLEX WITH COMPOUND 17
DATE LAST MODIFIED
9 Feb 2022
RELEASE
3 Nov 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.96
RESOLUTION RANGE LOW
44.78
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C01153
PDBe
6XRN
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P48736 | PIK3CG | SPODOPTERA FRUGIPERDA | HUMAN | PTDINS-3-KINASE SUBUNIT GAMMA,PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT GAMMA,P110GAMMA,PHOSPHOINOSITIDE-3-KINASE CATALYTIC GAMMA POLYPEPTIDE,SERINE/THREONINE PROTEIN KINASE PIK3CG,P120-PI3K | HUMAN | PTDINS-3-KINASE SUBUNIT GAMMA,PHOSPHATIDYLINOSITOL ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402