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GENERAL
TITLE
STRUCTURE OF HUMAN CGAS (K394E) BOUND TO THE NUCLEOSOME (FOCUSED REFINEMENT OF CGAS-NCP SUBCOMPLEX)
DATE LAST MODIFIED
9 Dec 2020
RELEASE
23 Sept 2020
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.15
RESOLUTION RANGE LOW
3.15
PUBMED ID
DOI
10.1038/S41586-020-2750-6
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q71DI3 HIST2H3A, HIST2H3C, H3F2, H3FM, HIST2H3D ESCHERICHIA COLI K-12 HUMAN
HISTONE H3/M,HISTONE H3/O
Mutations
P62805 H4C1, H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, ESCHERICHIA COLI K-12 HUMAN -- Mutations
Q16777 HIST2H2AC, H2AFQ ESCHERICHIA COLI K-12 HUMAN
HISTONE H2A-GL101,HISTONE H2A/Q
Mutations
O60814 H2BC12, H2BFT, HIRIP1, HIST1H2BK ESCHERICHIA COLI K-12 HUMAN
H2B K,HIRA-INTERACTING PROTEIN 1
Mutations
Q71DI3 HIST2H3A, HIST2H3C, H3F2, H3FM, HIST2H3D ESCHERICHIA COLI K-12 HUMAN
HISTONE H3/M,HISTONE H3/O
Mutations
P62805 H4C1, H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, ESCHERICHIA COLI K-12 HUMAN -- Mutations
Q16777 HIST2H2AC, H2AFQ ESCHERICHIA COLI K-12 HUMAN
HISTONE H2A-GL101,HISTONE H2A/Q
Mutations
O60814 H2BC12, H2BFT, HIRIP1, HIST1H2BK ESCHERICHIA COLI K-12 HUMAN
H2B K,HIRA-INTERACTING PROTEIN 1
Mutations
-- -- HUMAN --
-- -- HUMAN --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402