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GENERAL
TITLE
ENGINEERED CONJUGATION OF LYSINE-SPECIFIC MOLECULAR TWEEZERS WITH EXOS DERIVED PEPTIDIC INHIBITOR ENHANCE AFFINITY TOWARDS TARGET PROTEIN 14-3-3 THROUGH DITOPIC BINDING
DATE LAST MODIFIED
13 Oct 2021
RELEASE
31 Mar 2021
OBSOLETE
CLASSIFICATION
PEPTIDE BINDING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
59.9
PUBMED ID
DOI
10.1021/JACS.1C07095
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31947 SFN, HME1 ESCHERICHIA COLI HUMAN EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN HUMAN
EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN
Mutations
G3XDA1 -- -- PSEUDOMONAS AERUGINOSA -- PSEUDOMONAS AERUGINOSA -- Mutations
G3XDA1 -- -- PSEUDOMONAS AERUGINOSA -- PSEUDOMONAS AERUGINOSA -- Mutations
P31947 SFN, HME1 ESCHERICHIA COLI HUMAN EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN HUMAN
EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN
Mutations
P31947 SFN, HME1 ESCHERICHIA COLI HUMAN EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN HUMAN
EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN
Mutations
P31947 SFN, HME1 ESCHERICHIA COLI HUMAN EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN HUMAN
EPITHELIAL CELL MARKER PROTEIN 1,STRATIFIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402