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GENERAL
TITLE
X-RAY STRUCTURE OF FURIN IN COMPLEX WITH THE CANAVANINE-BASED INHIBITOR 4-GUANIDINOMETHYL-PHENYLACETYL-CANAVANINE-TLE-CANAVANINE- AMBA
DATE LAST MODIFIED
31 Mar 2021
RELEASE
17 Feb 2021
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65 2 2
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
47.2
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.0C00651

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P09958 FURIN, FUR, PACE, PCSK3 HOMO SAPIENS HUMAN DIBASIC-PROCESSING ENZYME,PAIRED BASIC AMINO ACID RESIDUE-CLEAVING ENZYME,PACE HUMAN
DIBASIC-PROCESSING ENZYME,PAIRED BASIC AMINO ACID ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402