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GENERAL
TITLE
SMALL-MOLECULE STABILIZER OF 14-3-3 AND THE CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN (CHREBP) PROTEIN-PROTEIN INTERACTION
DATE LAST MODIFIED
-
RELEASE
16 Sept 2020
OBSOLETE
CLASSIFICATION
STRUCTURAL PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
57.3
PUBMED ID
DOI
10.1038/S41467-020-17741-0
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31946 YWHAB ESCHERICHIA COLI HUMAN PROTEIN 1054,PROTEIN KINASE C INHIBITOR PROTEIN 1,KCIP-1 HUMAN
PROTEIN 1054,PROTEIN KINASE C INHIBITOR PROTEIN 1, ...
Mutations
Q9NP71 -- -- HUMAN CHREBP,CLASS D BASIC HELIX-LOOP-HELIX PROTEIN 14,BHLHD14,MLXINTERACTOR,MLX-INTERACTING PROTEIN-LIKE,WS BASIC-HELIX-LOOP-HELIXLEUCINE ZIPPER PROTEIN,WS-BHLH,WILLIAMS-BEUREN SYNDROME CHROMOSOMALREGION 14 PROTEIN HUMAN
CHREBP,CLASS D BASIC HELIX-LOOP-HELIX PROTEIN 14,B ...
Mutations
P31946 YWHAB ESCHERICHIA COLI HUMAN PROTEIN 1054,PROTEIN KINASE C INHIBITOR PROTEIN 1,KCIP-1 HUMAN
PROTEIN 1054,PROTEIN KINASE C INHIBITOR PROTEIN 1, ...
Mutations
Q9NP71 -- -- HUMAN CHREBP,CLASS D BASIC HELIX-LOOP-HELIX PROTEIN 14,BHLHD14,MLXINTERACTOR,MLX-INTERACTING PROTEIN-LIKE,WS BASIC-HELIX-LOOP-HELIXLEUCINE ZIPPER PROTEIN,WS-BHLH,WILLIAMS-BEUREN SYNDROME CHROMOSOMALREGION 14 PROTEIN HUMAN
CHREBP,CLASS D BASIC HELIX-LOOP-HELIX PROTEIN 14,B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402