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GENERAL
TITLE
STRUCTURE OF THE AMPA RECEPTOR GLUA2O LIGAND-BINDING DOMAIN (S1S2J) IN COMPLEX WITH THE COMPOUND (S)-1-(2'-AMINO-2'-CARBOXYETHYL)FURO[3,4- D]PYRIMIDIN-2,4-DIONE AT RESOLUTION 1.47A
DATE LAST MODIFIED
1 Jul 2020
RELEASE
3 Jun 2020
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
1.469
RESOLUTION RANGE LOW
47.54
PUBMED ID
DOI
10.1021/ACSCHEMNEURO.0C00195
PDBe
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Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P19491 | GRIA2, GLUR2 | ESCHERICHIA COLI BL21(DE3) | NORWAY RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B,GLUR-K2,GLUTAMATE RECEPTOR IONOTROPIC,AMPA 2,GLUA2BINDING DOMAIN OF GLUA2O. TRANSMEMBRANE REGIONS WERE GENETICALLYREMOVED AND REPLACED WITH A GLY-THR LINKER (RESIDUE 118-119). THESEQUENCE MATCHES DISCONTINOUSLY WITH THE REFERENCE DATABASE (UNPRESIDUES 413-527 AND 653-797, NUMBERING WITH SIGNAL PEPTIDE OF 21AMINO ACIDS). THE TWO FIRST RESIDUES (GLY, ALA) ARE CLONING REMNANTS. | NORWAY RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B, ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402