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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH THE DUAL INHIBITOR TW9
DATE LAST MODIFIED
18 Nov 2020
RELEASE
6 May 2020
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.05
RESOLUTION RANGE LOW
78.3
PUBMED ID
DOI
10.1002/IJC.33137
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60885 BRD4, HUNK1 ESCHERICHIA COLI HUMAN PROTEIN HUNK1 HUMAN
PROTEIN HUNK1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402