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GENERAL
TITLE
HIF PROLYL HYDROXYLASE 2 (PHD2/ EGLN1) IN COMPLEX WITH N-OXALYL GLYCINE (NOG), HIF-1ALPHA CODD (556-574) AND A RAPID-DERIVED CYCLIC PEPTIDE 3C (14-MER)
DATE LAST MODIFIED
-
RELEASE
30 Dec 2020
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.279
RESOLUTION RANGE LOW
55.69
PUBMED ID
DOI
10.1038/S41598-020-76307-8

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9GZT9 EGLN1, C1ORF12, PNAS-118, PNAS-137 ESCHERICHIA COLI BL21(DE3) HUMAN HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH-2,PROLYLHYDROXYLASE DOMAIN-CONTAINING PROTEIN 2,PHD2,SM-20 HUMAN
HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH- ...
Mutations
-- -- SYNTHETIC CONSTRUCT -- SYNTHETIC CONSTRUCT --
Q16665 -- -- HUMAN HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LOOP-HELIX-PAS PROTEIN MOP1,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 78,BHLHE78,MEMBER OF PAS PROTEIN 1,PAS DOMAIN-CONTAINING PROTEIN 8 HUMAN
HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402